ANNUAL BIOMARKER TESTING

Annual testing patterns for EGFR, ALK, PD-L1, and NGS are summarized by diagnosis year. The table below preserves the diagnosis-year-specific patient counts and testing coverage reported in the current ROOT HEALTH workbook.

Cohort definition: 38,154 patients with NSCLC, excluding stage 0, who received cancer-directed treatment at Samsung Medical Center. Data cutoff: September 18, 2026.

Annual Biomarker Testing in NSCLC

Diagnosis year 2008–2026, with overall totals shown in the final row.

Diagnosis Year Total NSCLC Patients EGFR Tested (N) EGFR Tested (%) ALK Tested (N) ALK Tested (%) PD-L1 Tested (N) PD-L1 Tested (%) NGS Tested (N) NGS Tested (%)
2026 1,597 1,503 94.1% 1,508 94.4% 1,521 95.2% 285 17.8%
2025 2,227 2,043 91.7% 2,021 90.7% 2,064 92.7% 441 19.8%
2024 1,714 1,563 91.2% 1,539 89.8% 1,569 91.5% 371 21.6%
2023 2,776 2,579 92.9% 2,574 92.7% 2,611 94.1% 655 23.6%
2022 2,652 2,462 92.8% 2,473 93.3% 2,503 94.4% 638 24.1%
2021 2,736 2,516 92.0% 2,545 93.0% 2,582 94.4% 628 23.0%
2020 2,497 2,332 93.4% 2,359 94.5% 2,388 95.6% 561 22.5%
2019 2,240 2,082 92.9% 2,084 93.0% 2,119 94.6% 435 19.4%
2018 2,414 2,227 92.3% 2,230 92.4% 1,963 81.3% 428 17.7%
2017 2,447 2,264 92.5% 2,271 92.8% 1,199 49.0% 233 9.5%
2016 2,188 1,979 90.4% 1,970 90.0% 725 33.1% 144 6.6%
2015 1,701 1,483 87.2% 1,459 85.8% 386 22.7% 76 4.5%
2014 2,059 1,786 86.7% 1,755 85.2% 307 14.9% 58 2.8%
2013 1,929 1,478 76.6% 1,471 76.3% 201 10.4% 45 2.3%
2012 1,583 834 52.7% 873 55.1% 127 8.0% 32 2.0%
2011 1,508 814 54.0% 659 43.7% 82 5.4% 24 1.6%
2010 1,394 664 47.6% 436 31.3% 62 4.4% 13 0.9%
2009 1,261 438 34.7% 187 14.8% 50 4.0% 16 1.3%
2008 1,231 318 25.8% 108 8.8% 39 3.2% 14 1.1%
Total 38,154 31,365 82.2% 30,522 80.0% 22,498 59.0% 5,097 13.4%
Back to Data